Article
Genetic analysis of cancer-implicated MicroRNA in ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2008
Bearfoot Jennifer L, Choong David Y H, Gorringe Kylie L, Campbell Ian G
Abstract excerpt
PURPOSE: There is accumulating evidence that microRNAs may function like classic tumor suppressor genes but little is known about their mechanism of inactivation in cancer cells. We investigated whether somatic mutations are a common mechanism of inactivation of microRNA genes in ovarian cancer....
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