Article
An allelic exchange system for compliant genetic manipulation of the select agents Burkholderia pseudomallei and Burkholderia mallei.
Gene - 1 Feb 2009
Hamad Mohamad A, Zajdowicz Sheryl L, Holmes Randall K, Voskuil Martin I
Abstract excerpt
Burkholderia pseudomallei and B. mallei are Gram-negative bacterial pathogens that cause melioidosis in humans and glanders in horses, respectively. Both bacteria are classified as category B select agents in the United States. Due to strict select-agent regulations, the number of antibiotic sele...
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