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Article

SBDS-deficiency results in specific hypersensitivity to Fas stimulation and accumulation of Fas at the plasma membrane.

Apoptosis : an international journal on programmed cell death - 1 Jan 2009

Watanabe Ken-Ichiro, Ambekar Chhaya, Wang Hanming, Ciccolini Amanda, Schimmer Aaron D, Dror Yigal

Abstract excerpt

Shwachman-Diamond syndrome (SDS) is an inherited disorder characterized by reduced cellularity in the bone marrow and exocrine pancreas. Most patients have mutations in the SBDS gene, whose functions are unknown. We previously showed that cells deficient in the SBDS protein are characterized by a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19009351
DOI: 10.1007/s10495-008-0275-9

Genes

SBDS
SDS
FADD
XIAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19009351-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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SBDS-deficiency results in specific hypersensitivity to Fas stimulation and accumulation of Fas at the plasma membrane.PMID 19009351Read ↗

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