Article
Molecular transmission networks and pre-treatment drug resistance among individuals with acute HIV-1 infection in Baoding, China.
PloS one - 1 Jan 2021
Shi Penghui, Chen Zhixia, Meng Juan, Su Miaomiao, Yang Xuegang, Fan Weiguang, Shi Haoxi, Gao Ying, Lu Xinli
Abstract excerpt
BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) genetic diversity and pre-treatment drug resistance (PDR) are major barriers to successful antiretroviral therapy (ART). In China, sexual intercourse is the most frequent route of HIV-1 transmission. However, few studies have analyzed PDR and transmission networks in detail among individuals in China with acute HIV-1 infection and their sexual contacts....
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