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Article

A myopathy-linked desmin mutation perturbs striated muscle actin filament architecture.

Molecular biology of the cell - 1 Feb 2009

Conover Gloria M, Henderson Syerra N, Gregorio Carol C

Abstract excerpt

Desmin interacts with nebulin establishing a direct link between the intermediate filament network and sarcomeres at the Z-discs. Here, we examined a desmin mutation, E245D, that is located within the coil IB (nebulin-binding) region of desmin and that has been reported to cause human cardiomyopa...

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Identifiers

PMID: 19005210
DOI: 10.1091/mbc.e08-07-0753
PMCID: PMC2633376

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19005210-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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