Article
Brain mast cells link the immune system to anxiety-like behavior.
Proceedings of the National Academy of Sciences of the United States of America - 18 Nov 2008
Nautiyal Katherine M, Ribeiro Ana C, Pfaff Donald W, Silver Rae
Abstract excerpt
Mast cells are resident in the brain and contain numerous mediators, including neurotransmitters, cytokines, and chemokines, that are released in response to a variety of natural and pharmacological triggers. The number of mast cells in the brain fluctuates with stress and various behavioral and endocrine states. These properties suggest that mast cells are poised to influence neural systems underlying behavior....
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