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Article

Epstein–Barr virus microRNAs reduce immune surveillance by virus-specific CD8 + T cells

3 Oct 2016

Abstract excerpt

Significance Most humans are infected for their lifetime with Epstein–Barr virus (EBV), which can cause cancer and other EBV-associated diseases. Infected individuals develop strong immune responses to this virus, in particular cytotoxic CD8 + T cells, but viral infection is never cleared nor is EBV eliminated from the body. This suggests that certain viral molecules might prevent effective elimination of...

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PMID: 27698133
DOI: 10.1073/pnas.1605884113

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