Article
Identification of an interferon-gamma-responsive element of a class II major histocompatibility gene in rat type 1 astrocytes.
Journal of neuroimmunology - 1 Mar 1991
Moses H, Sasaki A, Ting J P
Abstract excerpt
Interferon-gamma(IFN-gamma) has been shown to induce class II major histocompatibility complex (MHC) antigens on several cell types. Previous analysis of cell lines including a glioblastoma multiforme line by our laboratory has mapped an IFN-gamma-responsive element to the upstream - 141 to - 109 base pair (bp) region of the DRA promoter. Using deletion mutants, this report shows that this same general region...
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