Article
Phenotypic and functional heterogeneity of thymic and splenic lymphokine activated killer cells relative to ornithine sensitivity.
Cellular immunology - 1 Feb 1991
Mehrotra P, Bear H D, Susskind B M
Abstract excerpt
We have previously reported the selective inhibition of cytotoxic T lymphocytes (CTL) by 10 mM ornithine (ORN) relative to natural killer (NK) cell-derived lymphokine activated killer cells (LAK). To determine if this were due to differences in the progenitor cells or the type of stimulus, we use...
Topics
- Animals
- Antigens, Differentiation, T-Lymphocyte
- CD8 Antigens
- Cortisone
- Cytotoxicity, Immunologic
- Female
- G(M1) Ganglioside
- Glycosphingolipids
- Hematopoietic Stem Cells
- Interleukin-2
- Killer Cells, Lymphokine-Activated
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Ornithine
- Phenotype
- Recombinant Proteins
- Spleen
