Article
A potential role for colony-stimulating factor 1 in the genesis of the early endometriotic lesion.
Fertility and sterility - 1 Jan 2010
Jensen Jani R, Witz Craig A, Schenken Robert S, Tekmal Rajeshwar R
Abstract excerpt
OBJECTIVE: To investigate the role(s) of colony-stimulating factor 1 (CSF-1) on the development of early endometriosis in a murine model by comparing rate of lesion formation in mice [1] homozygous for a CSF-1 mutation versus syngeneic controls and [2] after treatment with imatinib, a commercially available tyrosine kinase inhibitor that alters interaction(s) between CSF-1 and its receptor, c-fms. DESIGN:...
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