Article
[Research of gene(s) involved in situs inversus. Initial results].
Archives des maladies du coeur et des vaisseaux - 1 May 1991
Alonso S
Abstract excerpt
Reverse Genetics consists in identifying the gene responsible for a hereditary condition, the biochemical mechanism of which is unknown. We have applied this approach to families recruited according to the following criteria: 1) at least two members of the family must be affected; 2) one of the t...
Topics
- Chromosome Inversion
- Consanguinity
- DNA Probes
- Female
- Genetic Complementation Test
- Genetic Linkage
- Genomic Library
- Heart Defects, Congenital
- Humans
- Hybridization, Genetic
- Lymphocyte Activation
- Male
- Mutation
- Pedigree
- Situs Inversus
