Article
BRCA1 5083del19 mutant allele selectively up-regulates periostin expression in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2008
Quaresima Barbara, Romeo Francesco, Faniello Maria C, Di Sanzo Maddalena, Liu Chang-Gong, Lavecchia Annamaria, Taccioli Cristian, Gaudio Eugenio, Baudi Francesco, Trapasso Francesco, Croce Carlo M, Cuda Giovanni, Costanzo Francesco
Abstract excerpt
PURPOSE: The aim of this study was to explore the gene expression pattern produced by the cancer-associated BRCA1 5083del19 founder mutation by using a microarray analysis. Such a mutation, identified in a subset of familial breast cancer patients, involves a deletion at the 3' end of the BRCA1 m...
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