Article
Oncostatin M regulates secretoglobin 3A1 and 3A2 expression in a bidirectional manner.
American journal of respiratory cell and molecular biology - 1 May 2009
Tomita Takeshi, Yamada Atsushi, Miyakoshi Masaaki, Kido Taketomo, Sheikh Faruk, Srisodsai Achara, Miyajima Atsushi, Donnelly Raymond P, Kimura Shioko
Abstract excerpt
Secretoglobin (SCGB) 3A1 and 3A2 are members of the small molecular weight secretoglobin gene superfamily. SCGB3A1 is a tumor suppressor gene, whereas SCGB3A2 has anti-inflammatory properties. Both genes are mainly expressed in the lung and trachea in mice. Whether the expression and/or function of these two genes are related is not known. Here we show that the expression of SCGB3A1 and SCGB3A2 are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
