Article
A quantitative assay to measure chromosome stability in Schizosaccharomyces pombe.
Molecular & general genetics : MGG - 1 Sept 1991
Bodi Z, Gysler-Junker A, Kohli J
Abstract excerpt
The fidelity of mitotic chromosome transmission in Schizosaccharomyces pombe was estimated quantitatively by using cycloheximide resistance as a means to select cells that had undergone chromosome loss or nondisjunction. We aimed to investigate the connection between recombination and mitotic chromosome stability. A number of mutants defective in mitotic recombination such as cdc17-L16, rec59-72, and rec50-25...
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