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Article

Cross-Linked Actin Networks (CLANs) in the Trabecular Meshwork of the Normal and Glaucomatous Human Eye In Situ

25 Feb 2009

Abstract excerpt

PURPOSE: A percentage of trabecular meshwork (TM) cells in tissue and organ culture have been shown to contain cross-linked actin networks (CLANs) when exposed to dexamethasone, as have TM cultures derived from glaucomatous individuals. The purpose of this study was to determine whether CLANs exist within TM cells in situ in tissue unmanipulated by culturing, thereby eliminating the possibility that CLANs are...

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PMID: 18952927
DOI: 10.1167/iovs.08-2706

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