Article
Identification of the endostyle as a stem cell niche in a colonial chordate.
Cell stem cell - 9 Oct 2008
Voskoboynik Ayelet, Soen Yoav, Rinkevich Yuval, Rosner Amalia, Ueno Hiroo, Reshef Ram, Ishizuka Katherine J, Palmeri Karla J, Moiseeva Elizabeth, Rinkevich Baruch, Weissman Irving L
Abstract excerpt
Stem cell populations exist in "niches" that hold them and regulate their fate decisions. Identification and characterization of these niches is essential for understanding stem cell maintenance and tissue regeneration. Here we report on the identification of a novel stem cell niche in Botryllus schlosseri, a colonial urochordate with high stem cell-mediated developmental activities. Using in vivo cell labeling,...
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