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Article

Gene expression profiling of ABC transporters in dermal fibroblasts of pseudoxanthoma elasticum patients identifies new candidates involved in PXE pathogenesis.

Laboratory investigation; a journal of technical methods and pathology - 1 Dec 2008

Hendig Doris, Langmann Thomas, Kocken Sarah, Zarbock Ralf, Szliska Christiane, Schmitz Gerd, Kleesiek Knut, Götting Christian

Abstract excerpt

Mutations in the ABCC6 gene, encoding the multidrug resistance-associated protein 6 (MRP6), cause pseudoxanthoma elasticum (PXE). This heritable disorder leads to pathological alterations in connective tissues. The implication of MRP6 deficiency in PXE is still unknown. Moreover, nothing is known...

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Source

Identifiers

PMID: 18936737
DOI: 10.1038/labinvest.2008.96

Genes

ABCC6
ABCA10
ABCA3
ABCA6
ABCA9
ABCB5
ABCC2
ABCC9
ABCD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18936737-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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