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Article

Polymerase chain reaction-based search for two alpha-globin gene mutations in India.

Hemoglobin - 1 Jan 2008

Bhattacharya Gargi, Sarkar Anjali A, Banerjee Debasish, Chandra Sarmila, Das Manikanchan, Dasgupta Uma B

Abstract excerpt

We have used restriction site-dependent polymerase chain reaction (PCR)-based methodology for detection of the alpha-globin polyadenylation (poly A) signal mutation, AATAAA>AATA- - and Hb Sun Prairie [alpha 130(H13)Ala-->Pro, GCT>CCT (alpha2)] mutation. The former mutation produces Hb H disease in the homozygous state and occurs frequently in the Indian population. It was detected in nine of 77 putative...

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PMID: 18932074
DOI: 10.1080/03630260802341620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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