Article
Effects of aneuploidy on genome structure, expression, and interphase organization in Arabidopsis thaliana.
PLoS genetics - 1 Oct 2008
Huettel Bruno, Kreil David P, Matzke Marjori, Matzke Antonius J M
Abstract excerpt
Aneuploidy refers to losses and/or gains of individual chromosomes from the normal chromosome set. The resulting gene dosage imbalance has a noticeable affect on the phenotype, as illustrated by aneuploid syndromes, including Down syndrome in humans, and by human solid tumor cells, which are high...
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