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Article

Immunity in a variable world.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 12 Jan 2009

Lazzaro Brian P, Little Tom J

Abstract excerpt

Immune function is likely to be a critical determinant of an organism's fitness, yet most natural animal and plant populations exhibit tremendous genetic variation for immune traits. Accumulating evidence suggests that environmental heterogeneity may retard the long-term efficiency of natural selection and even maintain polymorphism, provided alternative host genotypes are favoured under different environmental...

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Identifiers

PMID: 18926975
DOI: 10.1098/rstb.2008.0141
PMCID: PMC2666692

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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