Article
Cytodifferentiation of mouse mammary epithelial cells cultured on a reconstituted basement membrane reveals striking similarities to development in vivo.
Journal of cell science - 1 Jun 1991
Aggeler J, Ward J, Blackie L M, Barcellos-Hoff M H, Streuli C H, Bissell M J
Abstract excerpt
In the present study we provide evidence that the cytodifferentiation of primary mouse mammary epithelial cells within the alveolar-like structures formed after culture on a reconstituted basement membrane resembles development in vivo during late pregnancy and early lactation. During the first two days in culture on a basement membrane gel in the presence of lactogenic hormones, epithelial cells isolated from...
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