Article
Hereditary breast cancer: from bench to bedside.
Current opinion in oncology - 1 Nov 2008
De Grève Jacques, Sermijn Erica, De Brakeleer Sylvia, Ren Zhuo, Teugels Erik
Abstract excerpt
PURPOSE OF REVIEW: The proportion of breast cancers directly attributable to determinant hereditary factors is estimated to be 5-10%. A number of recent findings with regard to hereditary breast cancer should affect the criteria and scope of routine genetic testing and, soon, breast cancer therapy. RECENT FINDINGS: The number of genes causing genetic cancer has expanded, mostly with genes that encode proteins...
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