Article
Modulating effect of apolipoprotein E polymorphisms on secondary brain insult and outcome after childhood brain trauma.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Jan 2009
Lo T Y M, Jones P A, Chambers I R, Beattie T F, Forsyth R, Mendelow A D, Minns R A
Abstract excerpt
OBJECTIVE: The aim of this study was to determine the relationship between apolipoprotein E (APO E) alleles, the amount of cerebral perfusion pressure (CPP) insult and outcome in children after brain trauma. MATERIALS AND METHODS: In a prospective two-centre case-control study, the APO E genotypes of 65 critically ill children admitted after brain trauma were correlated with age-related CPP insult quantification,...
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