Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional analysis of mutations in the glucose-6-phosphate transporter that cause glycogen storage disease type Ib.

Molecular genetics and metabolism - 1 Dec 2008

Chen Shih-Yin, Pan Chi-Jiunn, Lee Soojung, Peng Wentao, Chou Janice Y

Abstract excerpt

The glucose-6-phosphate transporter (G6PT) deficient in glycogen storage disease type Ib is a phosphate (P(i))-linked antiporter capable of G6P: P(i) and P(i):P(i) exchanges. We previously characterized G6PT mutations by measuring G6P uptake activities in microsomes co-expressing G6PT and glucose-6-phosphatase-alpha. Here we report a new assay, based on reconstituted proteoliposomes carrying only G6PT, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to Chlorocebus aethiops

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to COS Cells

Share to Glucose-6-Phosphate

Share to Glycogen Storage Disease Type I

Share to Microsomes

Share to Monosaccharide Transport Proteins

Share to Phosphates

Source

Open in PubMed Open full text

Identifiers

PMID: 18835800
DOI: 10.1016/j.ymgme.2008.08.005
PMCID: PMC3422630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional analysis of mutations in the glucose-6-phosphate transporter that cause glycogen storage disease type Ib.PMID 18835800Read ↗

Structure-function analysis of the glucose-6-phosphate transporter deficient in glycogen storage disease type IbSemantic proximity Read ↗

Structure-function study of the glucose-6-phosphate transporter, an eukaryotic antiporter deficient in glycogen storage disease type Ib.Semantic proximity Read ↗

Homology modeling of the human microsomal glucose 6-phosphate transporter explains the mutations that cause the glycogen storage disease type Ib.Semantic proximity Read ↗

Mutations in the glucose-6-phosphatase-alpha (G6PC) gene that cause type Ia glycogen storage disease.Semantic proximity Read ↗

Glucose-6-phosphatase dependent substrate transport in the glycogen storage disease type-1a mouse.Semantic proximity Read ↗

Human variant glucose-6-phosphate transporter is active in microsomal transport.Semantic proximity Read ↗

The Biochemistry and Molecular Biology of the Glucose-6-Phosphatase System 1Semantic proximity Read ↗

The molecular basis of glycogen storage disease type 1a: structure and function analysis of mutations in glucose-6-phosphatase.Semantic proximity Read ↗

Mutations in the glucose-6-phosphatase gene that cause glycogen storage disease type 1a.Semantic proximity Read ↗

Identification of mutations in the gene for glucose-6-phosphatase, the enzyme deficient in glycogen storage disease type 1a.Semantic proximity Read ↗

Structural requirements for the stability and microsomal transport activity of the human glucose 6-phosphate transporter.Semantic proximity Read ↗

Glucose-6-phosphatase mutation G188R confers an atypical glycogen storage disease type 1b phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.