Article
Genetic variation and psoriasis.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia - 1 Oct 2008
Gudjonsson J E
Abstract excerpt
Psoriasis is a common chronic inflammatory skin disease with a strong genetic basis, characterized by complex alteration in epidermal growth and differentiation. The genetic basis of psoriasis has been appreciated for nearly 100 years, but only recently have several of the genetic variants involved in psoriasis pathogenesis been identified. These genetic variants so far identified are the HLA-Cw*0602 allele of...
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