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Article

The rate of protein secretion dictates the temporal dynamics of flagellar gene expression.

Molecular microbiology - 1 Nov 2008

Brown Jonathon D, Saini Supreet, Aldridge Christine, Herbert Jenny, Rao Christopher V, Aldridge Phillip D

Abstract excerpt

Flagellar gene expression is temporally regulated in response to the assembly state of the growing flagellum. The key mechanism for enforcing this temporal hierarchy in Salmonella enterica serovar Typhimurium is the sigma(28)-FlgM checkpoint, which couples the expression of the late flagellar (P(class3)) genes to the completion of the hook-basal body. This checkpoint is triggered when FlgM is secreted from the...

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Identifiers

PMID: 18811728
DOI: 10.1111/j.1365-2958.2008.06455.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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