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Mutations of maturity-onset diabetes of the young (MODY) genes in Thais with early-onset type 2 diabetes mellitus.

Clinical endocrinology - 1 Jun 2009

Plengvidhya Nattachet, Boonyasrisawat Watip, Chongjaroen Nalinee, Jungtrakoon Prapaporn, Sriussadaporn Sutin, Vannaseang Sathit, Banchuin Napatawn, Yenchitsomanus Pa-thai

Abstract excerpt

OBJECTIVE: Six known genes responsible for maturity-onset diabetes of the young (MODY) were analysed to evaluate the prevalence of their mutations in Thai patients with MODY and early-onset type 2 diabetes. PATIENTS AND METHODS: Fifty-one unrelated probands with early-onset type 2 diabetes, 21 of them fitted into classic MODY criteria, were analysed for nucleotide variations in promoters, exons, and exon-intron...

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PMID: 18811724
DOI: 10.1111/j.1365-2265.2008.03397.x

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