Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germ cell specific protein VASA is over-expressed in epithelial ovarian cancer and disrupts DNA damage-induced G2 checkpoint.

Gynecologic oncology - 1 Nov 2008

Hashimoto Hisashi, Sudo Tamotsu, Mikami Yoshiki, Otani Mieko, Takano Masaoki, Tsuda Hiroshi, Itamochi Hiroaki, Katabuchi Hidetaka, Ito Masaharu, Nishimura Ryuichiro

Abstract excerpt

OBJECTIVE: Cancer cells have characteristics, such as high telomerase activity and high levels of migration activity and proliferation, which are very similar to those of germ cell lineages. In this study, we examined the expression of VASA, a germ cell lineage specific marker and evaluated its clinical significance in epithelial ovarian cancer (EOC). METHODS: We investigated VASA expression in 75 EOC tissues by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to G2 Phase
Share to Gene Silencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to 14-3-3 Proteins

Share to DEAD-box RNA Helicases

Share to Down-Regulation

Share to Epithelial Cells

Share to Exonucleases

Share to Exoribonucleases

Source

Identifiers

PMID: 18805576
DOI: 10.1016/j.ygyno.2008.08.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Germ cell specific protein VASA is over-expressed in epithelial ovarian cancer and disrupts DNA damage-induced G2 checkpoint.PMID 18805576Read ↗

VASA Is a Specific Marker for Both Normal and Malignant Human Germ CellsSemantic proximity Read ↗

The human <i>VASA</i> gene is specifically expressed in the germ cell lineageSemantic proximity Read ↗

Germline factor DDX4 functions in blood-derived cancer cell phenotypes.Semantic proximity Read ↗

Sperm-Associated Antigen 9, a Novel Cancer Testis Antigen, Is a Potential Target for Immunotherapy in Epithelial Ovarian CancerSemantic proximity Read ↗

Revealing the inhibitory effect of VASH1 on ovarian cancer from multiple perspectivesSemantic proximity Read ↗

From Vascular Smooth Muscle Cells to Folliculogenesis: What About Vasorin?Semantic proximity Read ↗

Zebrafish vasa is required for germ-cell differentiation and maintenance.Semantic proximity Read ↗

Isolation of a DEAD-family protein gene that encodes a murine homolog of Drosophila vasa and its specific expression in germ cell lineage.Semantic proximity Read ↗

Expression and intracellular localization of mouse Vasa-homologue protein during germ cell developmentSemantic proximity Read ↗

Tissue-specific differentially methylated regions of the human VASA gene are potentially associated with maturation arrest phenotype in the testis.Semantic proximity Read ↗

VASA (DDX4) is a Putative Marker for Spermatogonia, Spermatocytes and Round Spermatids in StallionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.