Article
Role of fibrillin-1 genetic mutations and polymorphism in aortic dilatation in patients undergoing intracardiac repair of tetralogy of Fallot.
The Journal of thoracic and cardiovascular surgery - 1 Sept 2008
Chowdhury Ujjwal K, Mishra Anand K, Balakrishnan Prahlad, Sharma Sonika, Kabra Madhulika, Ray Ruma, Kalaivani Mani, Gupta Ruchika, Govindappa Raghu M, Subramaniam Ganapathy K
Abstract excerpt
OBJECTIVE: The purposes of this study were to identify the occurrence of fibrillin-1 gene polymorphisms or mutations in exons 24 to 28 and to identify the relationship between "DNA sequence variants" and aortic dilatation in the presence of abnormal aortic histopathology and other variables in patients undergoing intracardiac repair of tetralogy of Fallot. METHODS: Operatively excised full-thickness aortic wall...
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