Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Telomere maintenance and dysfunction predict recurrence in paediatric ependymoma

16 Sept 2008

Abstract excerpt

We have recently described the enzymatic subunit of telomerase (hTERT) as an important prognostic marker for paediatric ependymoma. Because of the lack of good, representative pre-clinical models for ependymoma, we took advantage of our large cohort of ependymoma patients, some with multiple recurrences, to investigate telomere biology in these tumours. Our cohort consisted of 133 ependymomas from 83 paediatric...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to DNA Repair Mechanisms
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18797459
DOI: 10.1038/sj.bjc.6604652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Telomere maintenance and dysfunction predict recurrence in paediatric ependymomaPMID 18797459Read ↗

Multifactorial analysis of predictors of outcome in pediatric intracranial ependymomaSemantic proximity Read ↗

Temporal and Clonal Progression in a Pediatric Ependymoma Patient Through Multiple TreatmentsSemantic proximity Read ↗

Telomerase activation in posterior fossa group A ependymomas is associated with dismal prognosis and chromosome 1q gain.Semantic proximity Read ↗

Portrait of Ependymoma Recurrence in Children: Biomarkers of Tumor Progression Identified by Dual-Color Microarray-Based Gene Expression AnalysisSemantic proximity Read ↗

Pediatric Ependymoma: Biological PerspectivesSemantic proximity Read ↗

Recent Advances in the Classification and Treatment of Ependymomas.Semantic proximity Read ↗

Resistance-promoting effects of ependymoma treatment revealed through genomic analysis of multiple recurrences in a single patient.Semantic proximity Read ↗

TERT Promoter Mutations but not the Alternative Lengthening of Telomeres Phenotype Are Present in a Subset of Ependymomas and Are Associated With Adult Onset and Progression to Ependymosarcoma.Semantic proximity Read ↗

Genomics and epigenetics: A study of ependymomas in pediatric patients.Semantic proximity Read ↗

Limitations of current in vitro models for testing the clinical potential of epigenetic inhibitors for treatment of pediatric ependymomaSemantic proximity Read ↗

Complex cytogenetic abnormalities including telomeric associations and MEN1 mutation in a pediatric ependymoma.Semantic proximity Read ↗

Predictors of outcome in an AIEOP series of childhood ependymomas: a multifactorial analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.