Article
Calcitonin gene-related peptide does not cause the familial hemiplegic migraine phenotype.
Neurology - 9 Sept 2008
Hansen Jakob Møller, Thomsen Lise Lykke, Olesen Jes, Ashina Messoud
Abstract excerpt
OBJECTIVE: The neuropeptide calcitonin gene-related peptide (CGRP) is a migraine trigger that plays a crucial role in migraine pathophysiology, and CGRP antagonism is efficient in the treatment of migraine attacks. Familial hemiplegic migraine (FHM) is a dominantly inherited subtype of migraine with aura associated with several gene mutations. FHM shares many phenotypical similarities with common types of...
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