Article
Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine.
Headache - 1 Apr 2011
Hansen Jakob M, Thomsen Lise L, Olesen Jes, Ashina Messoud
Abstract excerpt
BACKGROUND: Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP triggers migraine-like attacks in patients with migraine with aura and without aura. In contrast, patients with familial hemiplegic migraine (FHM) with known mutations did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine-like attacks in FHM patients without...
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