Article
A New Tetracycline Efflux Gene, tet (40), Is Located in Tandem with tet (O/32/O) in a Human Gut Firmicute Bacterium and in Metagenomic Library Clones
9 Sept 2008
Abstract excerpt
The bacterium Clostridium saccharolyticum K10, isolated from a fecal sample obtained from a healthy donor who had received long-term tetracycline therapy, was found to carry three tetracycline resistance genes: tet(W) and the mosaic tet(O/32/O), both conferring ribosome protection-type resistance, and a novel, closely linked efflux-type resistance gene designated tet(40). tet(40) encodes a predicted...
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