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UK epidemic Escherichia coli strains A-E, with CTX-M-15 beta-lactamase, all belong to the international O25:H4-ST131 clone.

The Journal of antimicrobial chemotherapy - 1 Dec 2008

Lau Siu Ha, Kaufmann Mary E, Livermore David M, Woodford Neil, Willshaw Geraldine A, Cheasty Tom, Stamper Katie, Reddy Suganya, Cheesbrough John, Bolton Frederick J, Fox Andrew J, Upton Mathew

Abstract excerpt

OBJECTIVES: Uropathogenic and invasive Escherichia coli O25:H4-ST131 isolates producing CTX-M-15 extended-spectrum beta-lactamase (ESBL) enzymes have recently been shown to be disseminated across the globe. In the UK, many CTX-M-15 ESBL-producing E. coli strains have been previously defined as belonging to the epidemic strains A-E, as determined by PFGE. The present study was carried out to define the...

Topics

Bacterial Typing Techniques
Cluster Analysis
DNA Fingerprinting
Electrophoresis, Gel, Pulsed-Field
Escherichia coli
Escherichia coli Infections
Genotype
Humans
Molecular Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

Serotyping

United Kingdom

beta-Lactamases

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Identifiers

PMID: 18779256
DOI: 10.1093/jac/dkn380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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UK epidemic Escherichia coli strains A-E, with CTX-M-15 beta-lactamase, all belong to the international O25:H4-ST131 clone.PMID 18779256Read ↗

Intercontinental emergence of Escherichia coli clone O25:H4-ST131 producing CTX-M-15.Semantic proximity Read ↗

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First Report of Prevalence of CTX-M-15-Producing Escherichia coli O25b/ST131 from Iran.Semantic proximity Read ↗

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CTX-M-15-H30Rx-ST131 subclone is one of the main causes of healthcare-associated ESBL-producing Escherichia coli bacteraemia of urinary origin in Spain.Semantic proximity Read ↗

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Emergence of Extended Spectrum-β-Lactamase-Producing Escherichia coli O25b-ST131Semantic proximity Read ↗

Emergence of clonal groups O1:HNM-D-ST59, O15:H1-D-ST393, O20:H34/HNM-D-ST354, O25b:H4-B2-ST131 and ONT:H21,42-B1-ST101 among CTX-M-14-producing Escherichia coli clinical isolates in Galicia, northwest Spain.Semantic proximity Read ↗

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