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Article

Co-occurrence of A1555G and G11778A in a Chinese family with high penetrance of Leber's hereditary optic neuropathy.

Biochemical and biophysical research communications - 7 Nov 2008

Zhang A-Mei, Jia Xiaoyun, Yao Yong-Gang, Zhang Qingjiong

Abstract excerpt

Co-occurrence of double pathogenic mtDNA mutations with different claimed pathological roles in one mtDNA is infrequent. It is tentative to believe that each of these pathogenic mutations would have its own deleterious effect. Here we reported one three-generation Chinese family with a high penet...

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Identifiers

PMID: 18775412
DOI: 10.1016/j.bbrc.2008.08.128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18775412-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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