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Article

Neurosurgical aspects of childhood hypophosphatasia.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Feb 2009

Collmann H, Mornet E, Gattenlöhner S, Beck C, Girschick H

Abstract excerpt

OBJECTIVE: Hypophosphatasia (HPP; MIM241510) is a rare inborn error of bone metabolism of recessive inheritance. It is caused by mutations in the gene encoding the tissue-nonspecific alkaline phosphatase. Apart from problems in bone mineralization, growth failure, and premature loss of decidual teeth, the infantile and the childhood types of HPP are associated with premature fusion of cranial sutures. PATIENTS:...

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Identifiers

PMID: 18769927
DOI: 10.1007/s00381-008-0708-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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