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Article

Identification of the key genes implicated in the transformation of OLP to OSCC using RNA-sequencing.

Oncology reports - 1 Apr 2017

Yang Qiaozhen, Guo Bin, Sun Hongying, Zhang Jie, Liu Shangfeng, Hexige Saiyin, Yu Xuedi, Wang Xiaxia

Abstract excerpt

Oral lichen planus (OLP) is a chronic inflammatory disease that may transform to oral squamous cell carcinoma (OSCC), while its carcinogenesis mechanisms are not entirely clear. This study was designed to identify the important genes involved in the malignant transformation of OLP to OSCC. After RNA-sequencing, the differently expressed genes (DEGs) in OLP vs. normal and OSCC vs. normal groups, respectively, were...

Read the complete abstract on PubMed

Topics

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Share to Carcinoma, Squamous Cell
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Gene Expression Regulation, Neoplastic

Share to Gene Regulatory Networks

Share to Lichen Planus, Oral

Share to Mouth Neoplasms

Share to Sequence Analysis, RNA

Source

Identifiers

PMID: 28259920
DOI: 10.3892/or.2017.5487

Genes

HES1
PER2
TSPAN33
GMPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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