Article
A target on the move: innate and adaptive immune escape strategies of hepatitis C virus.
Antiviral research - 1 Mar 2006
Thimme Robert, Lohmann Volker, Weber Friedemann
Abstract excerpt
Obligate intracellular parasites such as the hepatitis C virus (HCV) have to cope intensively with immune responses in order to establish persistent infection. Powerful antiviral mechanisms of the host act on several levels. The innate immune response is able to slow down viral replication and activate cytokines which trigger the synthesis of antiviral proteins. The adaptive immune system neutralizes virus...
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