Article
Genetic mechanisms in idiopathic epilepsies.
Developmental medicine and child neurology - 1 Sept 2008
Weber Yvonne G, Lerche Holger
Abstract excerpt
Idiopathic epilepsies are considered to be genetically determined. The inheritance can be monogenic and the detected mutation considered sufficient to cause the phenotype. In contrast, when the inheritance is complex, the epileptic phenotype is determined by several minor genetic defects that are much more difficult to discover. In recent years, an increasing number of mutations, mainly associated with rare...
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