Article
The molecular biology of genetic-based epilepsies.
Molecular neurobiology - 1 Feb 2014
Deng Hao, Xiu Xiaofei, Song Zhi
Abstract excerpt
Epilepsy is one of the most common neurological disorders characterized by abnormal electrical activity in the central nervous system. The clinical features of this disorder are recurrent seizures, difference in age onset, type, and frequency, leading to motor, sensory, cognitive, psychic, or autonomic disturbances. Since the discovery of the first monogenic gene mutation in 1995, it is proposed that genetic...
Topics
- Animals
- DNA, Mitochondrial
- Epilepsy
- Humans
- Mutation
- Potassium Channels, Voltage-Gated
- Voltage-Gated Sodium Channels