Article
Ion channel defects in idiopathic epilepsies.
Current pharmaceutical design - 1 Jan 2005
Lerche Holger, Weber Yvonne G, Jurkat-Rott Karin, Lehmann-Horn Frank
Abstract excerpt
Idiopathic epilepsies are genetically determined diseases of the central nervous system characterized by typical epileptic seizures and EEG abnormalities but not associated with structural brain lesions. In recent years, an increasing number of mutations associated with idiopathic epilepsy syndromes were identified in genes encoding subunits of voltage- or ligand-gated ion channels. These encouraging results...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.