Article
Optimal dose regimens of esomeprazole for gastric acid suppression with minimal influence of the CYP2C19 polymorphism.
European journal of clinical pharmacology - 1 Jan 2009
Lou Horng-Yuan, Chang Chun-Chao, Sheu Ming-Thau, Chen Ying-Chen, Ho Hsiu-O
Abstract excerpt
OBJECTIVE: In this pilot study, we attempted to determine the optimal dosage regimens of esomeprazole for treatment of GERD with minimal influence of the CYP2C19 polymorphism through a study of the pharmacokinetics and pharmacodynamics of esomeprazole given at 3 different dosage regimens with the...
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