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Article

Different dosage regimens of rabeprazole for nocturnal gastric acid inhibition in relation to cytochrome P450 2C19 genotype status.

Clinical pharmacology and therapeutics - 1 Oct 2004

Sugimoto Mitsushige, Furuta Takahisa, Shirai Naohito, Kajimura Masayoshi, Hishida Akira, Sakurai Masaharu, Ohashi Kyoichi, Ishizaki Takashi

Abstract excerpt

OBJECTIVE: For the treatment of gastroesophageal reflux disease, intragastric pH should be lower than 4.0 for no more than 4 hours a day (<16.7%). We aimed to develop optimal dosage regimens for rabeprazole to control nocturnal acidity in relation to cytochrome P450 (CYP) 2C19 genotypes. METHODS:...

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Identifiers

PMID: 15470328
DOI: 10.1016/j.clpt.2004.06.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15470328-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Different dosage regimens of rabeprazole for nocturnal gastric acid inhibition in relation to cytochrome P450 2C19 genotype status.PMID 15470328Read ↗

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