Article
Fibrin promotes proliferation and matrix production of intervertebral disc cells cultured in three-dimensional poly(lactic-co-glycolic acid) scaffold.
Journal of biomaterials science. Polymer edition - 1 Jan 2008
Sha'ban Munirah, Yoon Sun Jung, Ko Youn Kyung, Ha Hyun Jung, Kim Soon Hee, So Jung Won, Idrus Ruszymah Bt Hj, Khang Gilson
Abstract excerpt
Previously, we have proven that fibrin and poly(lactic-co-glycolic acid) (PLGA) scaffolds facilitate cell proliferation, matrix production and early chondrogenesis of rabbit articular chondrocytes in in vitro and in vivo experiments. In this study, we evaluated the potential of fibrin/PLGA scaffold for intervertebral disc (IVD) tissue engineering using annulus fibrosus (AF) and nucleus pulposus (NP) cells in...
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