Article
Development of human single-chain antibodies against SARS-associated coronavirus.
Intervirology - 1 Jan 2008
Leung K M, Feng D X, Lou Jianlong, Zhou Yu, Fung K P, Waye Mary M Y, Tsui Stephen K W, Chan Paul K S, Marks James D, Pang S F, Kan Y W
Abstract excerpt
The outbreak of severe acute respiratory syndrome (SARS), caused by a distinct coronavirus, in 2003 greatly threatened public health in China, Southeast Asia as well as North America. Over 1,000 patients died of the SARS virus, representing 10% of infected people. Like other coronaviruses, the SARS virus also utilizes a surface glycoprotein, namely the spike protein, to infect host cells. The spike protein of...
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