Article
Increase in quantitative variation after exposure to environmental stresses and/or introduction of a major mutation: G x E interaction and epistasis or canalization?
Genetics - 1 Sept 2008
Zhang Xu-Sheng
Abstract excerpt
Why does phenotypic variation increase upon exposure of the population to environmental stresses or introduction of a major mutation? It has usually been interpreted as evidence of canalization (or robustness) of the wild-type genotype; but an alternative population genetic theory has been suggested by J. Hermisson and G. Wagner: "the release of hidden genetic variation is a generic property of models with...
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