Article
Triple genetic identities for the complete hydatidiform mole, placenta and co-existing fetus after transfer of a single in vitro fertilized oocyte: case report and possible mechanisms.
Human reproduction (Oxford, England) - 1 Dec 2008
Hsu Chao-Chin, Lee I-Wen, Su Mei-Tzu, Lin Yi-Chien, Hsieh Christine, Chen Pei-Yi, Tsai Hung-Wen, Kuo Pao-Lin
Abstract excerpt
We found different genotypes for the complete hydatidiform mole (CHM), placenta and co-existing fetus derived from a single in vitro fertilized human oocyte by the analysis of short tandem repeat (STR) DNA markers. The molar tissue was found to be heterozygously androgenetic. The fetus and placenta contained identical maternal, but different paternal genomes. Two models were proposed to account for the...
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