Article
Relationship between mixed chimerism and rejection after bone marrow transplantation in thalassaemia.
1 Jul 2008
Abstract excerpt
BACKGROUND: Thalassaemia is a genetic disease that requires a hypertransfusion regimen to treat the anaemia caused by enhanced red blood cell destruction. The only radical cure for thalassaemia is to correct the genetic defect by bone marrow transplantation from an HLA-identical donor capable of producing and maintaining a normal haemoglobin level in the recipient. Complete donor haematopoiesis is not essential...
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