Article
Role of the Campylobacter jejuni Cj1461 DNA methyltransferase in regulating virulence characteristics.
Journal of bacteriology - 1 Oct 2008
Kim Joo-Sung, Li Jiaqi, Barnes If H A, Baltzegar David A, Pajaniappan Mohanasundari, Cullen Thomas W, Trent M Stephen, Burns Christopher M, Thompson Stuart A
Abstract excerpt
Mutation of the cj1461 predicted methyltransferase gene reduced the motility of Campylobacter jejuni 81-176. Electron microscopy revealed that the mutant strain had flagella but with aberrant structure. The Deltacj1461 mutant was sevenfold more adherent to but 50-fold less invasive of INT-407 human epithelial cells than the wild type.
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