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Article

Genetic variants in RUNX3 and risk of bladder cancer: a haplotype-based analysis.

Carcinogenesis - 1 Oct 2008

Zhang Zhizhong, Wang Shizhi, Wang Meilin, Tong Na, Fu Guangbo, Zhang Zhengdong

Abstract excerpt

Transforming growth factor-beta (TGF-beta) is a multifunctional growth factor that plays important roles in many biological processes, whereas RUNX3 is a target of TGF-beta-mediated tumor suppressor pathway. In humans, RUNX3 inactivation may lead to the cancer development, including bladder cancer. To determine whether the RUNX3 polymorphisms are associated with risk of bladder cancer, we conducted a case-control...

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Identifiers

PMID: 18684727
DOI: 10.1093/carcin/bgn183

Genes

RUNX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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